Figure 9.

Diagrammatic representation of the postulated mechanism of action of EtOH to suppress NMDA-stimulated LHRH release. For explanation, see Discussion. β-end, β-endorphin; μR, μ-opioid receptor; GABA-n, GABA neuron; NO-n, NO-ergic neuron; NE-n, noradrenergic neuron; α_1r, α₁ adrenergic receptor; NMDA-r, NMDA receptor; Glut-n, glutamergic neuron; LHRH-n, LHRH neuronal terminal; lipids, membrane phospholipids; PLA₂, phospholipase A₂; GC, guanylate cyclase; AC, adenylate cyclase. Solid arrow indicates stimulation. Dashed arrow indicates inhibition.