Table 3.

PPROM and delivery characteristics. PPROM: preterm premature rupture of membranes; HAART: highly active antiretroviral therapy; AZT: zidovudine; C/S: cesarean delivery; IUFD: intrauterine fetal demise; NSVD: spontaneous vaginal delivery; N/A: data not available.

Patient

Gestational

Viral load at

CD4 count

HAART at PPROM

Intrapartum

Latency antibiotics

Interval to

Viral load at

Indication for delivery

Mode of delivery

Clinical

Histologic

Histologic funisitis

age at

PPROM

at PPROM

AZT therapy

delivery

delivery

chorio

chorio

PPROM

(copies/mL)

(abs/mm3)

(days)

(days)

(copies/mL)

amnionitis

amnionits

1

30 5/7

1809

508

Combivir

Yes

No

1

1809

Labor prior classical

C/S

No

No

No

(2 hours)

2

17 2/7

7319

724

None

None

No

92

179

IUFD

SVD

No

Unknown

Unknown

indicated

3

30 2/7

< 50

684

Neviripine Lamivudine Stavudine

No (adverse reaction)

Yes

5

< 50

Chorio nonreassuring fetal status

C/S

Yes

Yes

Yes

4

31 4/7

< 50

407

Combivir

Yes

Yes

2

< 50

Chorio

SVD

Yes

Yes

Yes

Neviripine

(2 days)

5

24 2/7

3710

312

Combivir

Yes

No

10

971

Labor

C/S

No

Yes

Yes

AZT (2 days);

nonreassur-

HAART (8 days);

ing fetal

AZT (4 hours)

status

6

31 0/7

N/A

459

None

None

Yes

3

N/A

Chorio

SVD

Yes

N/A

N/A

7

23 4/7

N/A

N/A

None

Yes

Yes

7

N/A

Labor

SVD

No

N/A

N/A

(3 days)