Table 1.

Up to date, more than one hundred intronic microRNAs have been identified; however, only a few of them were tested

miRNA	Species	Host gene (intron) [#]	Target gene(s)
Intronic microRNA
miR-2a, −b2	Worm	Spi
miR-7b	Mammal	pituitary gland specific factor 1A (2) [NM174947]	paired mesoderm homeobox protein 2b; HLHm5
miR-10b	Mammal	homeobox protein HOX-4 (4)
miR-11	Drosophila	E2F
miR-13b2	Drosophila	CG7033
miR-15b, −16-2	Mammal	chromosome-associated polypeptide C
miR-25, −93, −106b	Mammal	CDC47 homolog (13)
miR-26a1, −26a2, −26b	Vertebrate	nuclear LIM interactor-interacting factor 1, 2, 3
miR-28	Human	LIM domain-containing preferred translocation parterner in lipoma [NM005578]
miR-30c1, −30e	Mammal	nuclear transcription factor Y subunit γ (5)	transcription factor HES-1; PAI-1 mRNA-binding protein
miR-33	Vertebrate	sterol regulatory element binding protein-2 (15)	RNA-dependent helicase p68; NAG14 protein
miR-101b	Human	RNA 3′-terminal phospate cyclase-like protein (8)
miR-103, −107	Human	pantothenate kinase 1, 2, 3
miR-105-1, −105-2, −224	Mammal	γ-aminobutyric-acid receptor α-3 subunit precursor, ɛ subunit precursor
miR-126, −126*	Mammal	EGF-like, Notch4-like, NEU1 protein (6) [NM178444]
miR-128b	Mammal	cAMP-regulated phospho-protein 21 (11)
miR-139	Mammal	cGMP-dependent 3′,5′-cyclic phosphodiesterase (2)
miR-140	Human	NEDD4-like ubiquitin-protein ligase WWP2 (15)
miR-148b	Mammal	coatomer ζ-1 subunit
miR-151	Mammal
miR-152	Human	coatomer ζ-2 subunit	N-myc proto-oncogene protein; noggin precursor
miR-153-1, −153-2	Human	protein-tyrosine phosphatase N precursors
miR-208	Mammal	myosin heavy chain, cardiac muscle α isoform (28)
miR-218-1, −218-2	Human	Slit homolog proteins [NM003062]

As listed above, the function and mechanism of some of the most early found intronic miRNAs are currently under investigation.

^*represents the counterpart of the sense miR-126 sequence, and # denotes the GenBank accession number.