Table 1.
Names of relevant functionally similar genes in fission yeast, budding yeast, and humans
| Fission yeast | Humans | Budding yeast | Protein function |
|---|---|---|---|
| dfp1 | DBF4/ASK1 | DBF4 | Initiation of replication |
| hsk1 | CDC7 | CDC7 | Initiation of replication |
| cdc18 | CDC6 | CDC6 | Formation of pre-replication complex |
| orp2 | ORC2 | ORC2 | Formation of pre-replication complex |
| orp5 | ORC5 | ORC5 | Formation of pre-replication complex |
| pku70 | KU70 | YKU70 | Non-homologous end joining |
| rad32 | MRE11 | MRE11 | Homologous recombination |
| rqh1 | BLM | SGS1 | Replication fork stability |
| rhp9/crb2 | BRCA1 or 53BP1 | RAD9 | DNA damage checkpoint |
| rad3 | ATR | MEC1 | DNA damage and replication checkpoints |
| cds1 | CHK2/CDS1 | RAD53 | DNA replication checkpoint (fission yeast) |
| cdc2 | CDK1/CDC2 | CDC28 | Cyclin-dependent kinase |
This table contains the genes discussed in the text for which the fission yeast name differs from the human name.