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. 2006 Sep 22;2:25. doi: 10.1186/1745-0179-2-25

Table 1.

Association between risk factors and polypharmacy

Mono Pharmacy (n = 49) Poly Pharmacy (n = 54) Unadjusted OR df P Value Adjusted ORa 95% CI for OR P Value
n % n %
Demographic
Gender
 Male 25 24.3 31 30.1 1.2 1 0.5 1.2 0.5 2.7 0.6
 Female 24 23.3 23 22.3
Illness
Diagnosis
 Psychosis 24 23.3 12 11.7 1.4 1 0.2 1.6 0.8 3.2 0.1
 Mood 20 19.4 35 34
 Others 5 4.9 7 6.8
Comorbidity
 Yes 29 28.2 35 34 1.2 1 0.5 1.3 0.6 3.0 0.4
 No 20 19.4 19 18.4
Psychotic symptom
 Yes 27 26.2 33 32 1.2 1 0.5 1.2 0.5 2.8 0.5
 No 22 21.4 21 20.4
Treatment
Nonpharmacological
 Yes 33 32 17 16.5 4.5 1 0.001 4.7 2.0 11.1 0.001
 No 16 15.5 37 35.9
PRN medication
 Yes 19 18.7 8 7.8 3.6 1 0.007 3.3 1.2 8.8 0.01
 No 30 29.1 46 44.7
Physical restraint
 Yes 39 37.9 32 31.1 0.4 1 0.02 0.3 0.1 0.8 0.02
 No 10 20.4 22 40.7
Side effect
 Yes 35 18.4 27 21.4 1.5 1 0.3 1.9 0.7 4.7 0.2
 No 19 34 22 26.2

a Adjusted for age, number of days as inpatient, amount of antipsychotic in chlorpromazine equivalent.