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ETA Receptor Antagonist and Docetaxel Treatment in Mice Bearing PPC-1 Xenograft Tumors.
| Treatment | Baseline Tumor (mm3) | Final Tumor Volume (mm3) | Doubling Time (mm3/day) |
| Vehicle | 63.73 | 690.5 ± 165.0 | 5.93 |
| ABT-627 | 54.58 | 775.5 ± 164.2 | 5.36 |
| Docetaxel | 55.57 | 657.4 ± 158.3 | 5.41 |
| ABT-627 + docetaxel | 55.1 | 321.7 ± 76.1* | 8.29* |
Statistically different from all other treatment groups (P < .05).
