Table 4.

Haplotype analysis of intragenic BRCA2 polymorphisms associated with the 9106C>T BRCA2 mutation.

Polymorphisms		Family 25							Isolated cases
Position	Nucleotide change	BR22	BR23	BR99	BR100	BR101	BR102	BR103	BR175	BR342	TBL 38
		M	w.t.	w.t.	M	M	M	w.t.	M	M	M
EX2	203G>A	G>A	G-G	G>A	A-A	A-A	A-A	G-G	G>A	G>A	G>A
INTR8	IVS8+56C>T	C-C	C-C	C>T	C>T	C-C	C-C	C-C	C>T	C-C	C>T
EX10B	1342A>C	A>C	C-C	A-A	A-A	A-A	A-A	C-C	A-A	A-A	A-A
EX11-J	3624A>G	A>G	A-A	A>G	G-G	G-G	G-G	A-A	A>G	A>G	A>G
EX11K	4035T>C	T-T	T-T	T>C	T-T	T-T	T-T	T-T	T-T	T>C	T-T
INTR11Q	IVS11+80del4	-4/4	4/4	-4/4	-4/-4	-4/4	-4/-4	4/4	-4/4	-4/4	-4/4
EX14A	7470A>G	A>G	A-A	A>G	G-G	G-G	G-G	A-A	A>G	A>G	A>G
INTR17	IVS16-14T>C	T>C	T>C	T>C	C-C	C-C	C-C	T>C	C-C	T>C	T>C

M: mutated; w.t.: wild-type; numbers in bold indicate the shared allele.