The effect of KCl and NaCl on purified seHAS was determined using the normal assay conditions to assess HAS activity described in Methods, except that two buffer concentrations were used: 25 mM KHPO4 (○,•) and 50 mM KHPO4 (□,▪) with varying NaCl (○,□) and KCl (•,▪) concentrations from 0–1.0 M. Kinetics were linear with respect to time and enzyme concentration under all conditions.