Table 3.
Rates of all insertions and deletions in CAK revertant clones
| CAK-pCT1 [(+1) reading frame]
|
CAK-pRTM2 [(−1) reading frame]*
|
||||
|---|---|---|---|---|---|
| hygR clone no. | Insertion rate | Deletion rate | hygR clone no. | Insertion rate | Deletion rate |
| 6 | 1.3 × 20−5 | 1.6 × 10−6 | 1 | 3.3 × 10−6 | 7.1 × 10−6 |
| 8 | 3.9 × 10−5 | 7.1 ×10−6 | 2 | 7.9 × 10−6 | 8.5 × 10−6 |
| 9 | 7.3 × 10−5† | 9.8 × 10−6† | 6 | 7.5 × 10−6 | 7.5 × 10−6 |
| 11 | 1.2 × 10−5† | 7.2 × 10−6† | |||
Rates are expressed as mutations per cell per generation.
*
Based on data from ref. 19.
†
Clones containing two copies of the microsatellite sequence; mutation rates in these clones have been divided by 2 to determine rates per microsatellite sequence.