Table 1.
List of selected PTS and ORE candidate genes
| Gene | PTS1 | ORE | Distribution | pex | onu | lys |
|---|---|---|---|---|---|---|
| YCR005C/CIT2 | SKL | Yes | Peroxisomal* | No | No | No |
| YKR009C/FOX2 | SKL | Yes | Peroxisomal | ND | ND | ND |
| YDR256C/CTA1 | SKF | Yes | Peroxisomal | ND | ND | ND |
| YDL078C/MDH3 | SKL | Yes | Peroxisomal | ND | ND | ND |
| YML024W/CAT1 | AKL | Yes | Peroxisomal | ND | ND | ND |
| YBR222C/PCS60 | SKL | Yes | Peroxisomal* | ND | ND | ND |
| YNL202W/SPS19 | SKL | Yes | Peroxisomal* | No | P | No |
| YIR027C/AAT2 | AKL | No | Peroxisomal* | No | P | No |
| YNL117W/MLS1 | SKL | No | Peroxisomal* | No | P | No |
| YIR031C/MLS2 | SKL | No | Cytoplasmic* | No | No | No |
| YIR034C/LYS1 | SRL | No | Peroxisomal* | No | No | Yes |
| YDR234W/LYS4 | SQL | No | Peroxisomal* | No | No | Yes |
| YGR077C | SKL | No | Peroxisomal* | Yes | Yes | P |
| YGL184C | SKL | NO | Peroxisomal* | No | No | No |
| YNL009W | SKL | Yes | Peroxisomal* | No | P | No |
| YGR154C | SKL | No | Peroxisomal* | No | No | No |
| YBR204C | SKL | No | Lipid Droplet* | ND | ND | ND |
| YLR109W | AHL | No | Cytoplasmic* | ND | ND | ND |
| YEL029C | ARL | No | Cytoplasmic* | ND | ND | ND |
| YIL094C | SRL | No | Cytoplasmic* | ND | ND | ND |
| YDR449C | SKL | No | Nuclear* | ND | ND | ND |
| YGL067W | SHL | No | ND | ND | ND | ND |
| YMR259C | SQL | No | ND | ND | ND | ND |
| YBL071C | SHL | No | ND | ND | ND | ND |
| YBR012C | SRL | No | ND | ND | ND | ND |
| YJR019C | No | Yes | Peroxisomal* | No | P | No |
| YLR284C | No | Yes | Peroxisomal* | No | P | No |
| YOR180C | No | Yes | Peroxisomal* | No | P | No |
| YPR128C | No | Yes | Peroxisomal* | No | No | No |
| YOL044W | No | Yes | Peroxisomal* | Yes | Yes | P |
PTS1 refers to the form or absence of PTS1 in the protein. ORE refers to whether the corresponding gene contains a consensus ORE sequence. Proteins that were localized in this study are marked by an asterisk, and those proteins that had not previously been localized are in bold. Mutants that display defects in peroxisome biogenesis were designated pex, mutants defective in growth on oleic acid were designated onu, and lysine auxotrophs were designated lys. ND, not determined; no means it is not a mutant; yes means it is a mutant; and P means that the defect appears to be partial.