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. Author manuscript; available in PMC: 2006 Oct 3.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2005 Sep;32(9):1115–1123. doi: 10.1007/s00259-005-1853-5

Table 5.

Comparison between experimental and theoretical blood levels (%ID/g) in pretargeting with 30 μg MN14-MORF and 0.30 μg labeled cMORF

Blood level of labeled cMORF
Pretargeting interval Blood level of MN14-MORFa Theoreticalb Experimental
2 days 1.94 1.38 1.27±0.17
3 days 1.02 0.77 0.93±0.08
4 days 0.53 0.44 0.58±0.13
a

Calculated from the antibody blood clearance curve

b

The theoretical blood level of labeled cMORF (%ID/g)=the blood level of antibody-MORF (%ID/g)×dose of antibody-MORF ÷ MWantibody×gmp×MWcMORF ÷ dose of labeled cMORF+background blood level of free labeled cMORF=the blood level of antibody-MORF (%ID/g)×30 μg÷160,000×0.17×6331÷0.30 μg+0.08. The 0.08 is from reference [18]