Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Survival curve of mice harboring germ-line mutations in p53 and/or decorin. The graph summarizes the survival of p53−/− Dcn−/− (●, n = 58) relative to p53−/− Dcn+/− (○, n = 28), and p53+/+ Dcn−/− (▵, n = 68). The mean survival age (T50) was ≈4 and ≈6 months for the p53−/− Dcn−/− and p53−/− Dcn+/− genotype, respectively. None of the p53+/+ Dcn−/− animals developed tumors or needed to be sacrificed for ill health during the 9-month period of observation.
