Table 4.
Promoter analysis of 37 pairs of Aroclor 1254-regulated genes which are directly neighbored.
| FIRST GENE (REFSEQ ACCESSION NUMBER) | FIRST GENE (AHR BINDING SITES) | FIRST GENE (BINDING SITES OF OTHER TFS) | SECOND GENE (REFSEQ ACCESSION NUMBER) | SECOND GENE (AHR BINDING SITES) | SECOND GENE (BINDING SITES OF OTHER TFS) |
| NM_003928 | - | - | NM_015582 | n.d.* | n.d.* |
| NM_005334 | - | NFKB | NM_003492 | 1 | ATF3, SP2 |
| NM_001643 | - | PPARG2 | NM_032174 | 1 | - |
| NM_021642 | 1 | - | NM_002155 | - | NFKB |
| NM_005807 | - | - | NM_003292 | - | SP2 |
| NM_006623 | - | - | NM_005518 | - | PPARG2 |
| NM_002061 | 1 | SP2 | NM_000350 | - | - |
| NM_144631 | 2 | RFXANK | NM_002707 | 1 | PPARG2 |
| NM_005911 | - | SP2, PPARG2 | NM_000821 | 1 | PPARG2 |
| NM_016467 | - | PPARG2 | NM_000534 | - | NFKB |
| NM_022173 | 1 | - | NM_016297 | 1 | RFXANK, SP2 |
| NM_006590 | 1 | - | NM_000542 | - | NRF1, PPARG2 |
| NM_005141 | - | - | NM_000508 | - | - |
| NM_000508 | - | - | NM_000509 | - | - |
| NM_007104 | - | - | NM_003214 | 1 | SP2 |
| NM_138446 | 1 | - | NM_006547 | - | BHLHB2 |
| NM_003235 | - | - | NM_006748 | - | - |
| NM_001261 | - | NFKB | NM_004957 | - | PBX1, SP2 |
| NM_005564 | - | NFKB | NM_024112 | - | SP2 |
| NM_005489 | - | SP2 | NM_001261 | - | - |
| NM_004376 | - | NFKB | NM_015960 | - | PPARG2 |
| NM_005271 | 5 | BHLHB2 | NM_019054 | 3 | - |
| NM_001572 | - | SP2, NFKB | NM_021924 | 1 | SP2 |
| NM_052854 | - | SP2 | NM_003646 | - | SP2, PPARG2 |
| NM_006169 | - | RFXANK | NM_019021 | 1 | PPARG2 |
| NM_021640 | - | - | NM_015665 | - | NFKB |
| NM_003348 | 1 | - | NM_014050 | - | - |
| NM_002937 | - | PPARG2 | NM_001145 | - | - |
| NM_006599 | - | NFKB, BHLHB2 | NM_000903 | 1 | NRF1 |
| NM_003562 | 1 | RFXANK | NM_015528 | 1 | NFKB, RFXANK |
| NM_002544 | 1 | - | NM_006495 | - | - |
| NM_018952 | - | NFKB, RFXANK | NM_004502 | 2 | RFXANK, BHLHB2 |
| NM_007292 | 2 | NFKB, BHLHB2 | NM_001258 | - | PPARG2 |
| NM_005359 | - | - | NM_016626 | 1 | SP2 |
| NM_032377 | - | RFXANK | NM_001611 | 2 | BHLHB2, PPARG2 |
| NM_018270 | 2 | - | NM_007346 | - | RFXANK, BHLHB2 |
| NM_002626 | 2 | SP2 | NM_004928 | 1 | SP2 |
* Promoter sequence was not available
ATF3: activating transcription factor 3, function unknown; BHLHB2: basic helix-loop-helix domain containing, class B2, anti-apoptosis, oncogenesis, hypoxia-induced; NFKB1: Nuclear Factor kappa B1, cytokine or stress-activated; NRF1: nuclear respiratory factor 1, cell growth, development; PPARG2: Peroxisome proliferator-activated receptor gamma, adipocyte differentiation, obesity, diabetes and cancer; RFXANK: regulatory factor X-associated ankyrin-containing protein, controls the cell type specificity and inducibility of MHC class II gene expression; SP2: Sp2 transcription factor, binds to GC box promoters elements.