Figure 2.

Native and native-like structures of tetrameric KcsA. (a) View of the crystal structure seen from the extracellular side; the monomers are differently colored. (b) and (c) The superimposition between native (green color) and the best native-like (violet color) structures is shown. The native-like structure shown in this figure, i.e. the A-Bs1-Cs500-Ds2 tetramer, has been achieved through a dipole moment-based reorientation approach (see Table 1 and Figure 6). In panel (b) the superimposed structures are seen from the extracellular side, whereas in panel (c) the structures are seen in a direction parallel to the membrane surface. Drawings were done by means of the software PYMOL 0.98 [39].