Figure 3.

The effects of antagonistic analogs on [³H]thymidine incorporation into DNA of cultured human cancer cell lines. The cells were exposed to MZ-4-71 or MZ-5-156 for 24 hours, [³H]thymidine was added, and the incubation was continued for 4 hours. Relative [³H] activities of the washed cells (mean ± SEM) are plotted relative to those of control groups. Significant differences from the control groups are indicated. ∗, 0.05 > P > 0.01; ∗∗, P < 0.01, two-tailed Student’s t test.