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. 1999 Mar 16;96(6):3108–3113. doi: 10.1073/pnas.96.6.3108

Figure 4.

Figure 4

Epitope mapping of mAb 39–44 and mAb 56–61. (Left) Part of the sequence of TTRs53–55 with the defined epitopes boxed. The sequenced fragments obtained by screening the DNA fusion library as described in Materials and Methods are depicted as lines. (Right) A space-filling model of a dimer of TTR, by using the Molscript program, with the minimal epitopes defined by mAb 39–44 and mAb 56–61 depicted. The view is along the β-strand direction. The epitopes seem to be embedded in the TTR monomer.