Table 1.

Comparisons of clinical and physiological characteristics between women and men matched by their predicted FEV₁

Clinical & Physiological Characteristics	Men (n = 73)	Women (n = 73)	p Value
Age (years old)	63 ± 8*	56 ± 11*	<0.001
Age range	47–77	37–79
Pack-years history	69 ± 26*	47 ± 22*	<0.001
BMI (kg/m2)	27 ± 4*	25 ± 7*	0.04
BMI ≤ 21(%)	6	32	0.007
Charlson Index (points)	3 (1–6) +	1 (1–3) +	<0.001
MMRC (points)
0–2 (%)	93	71	<0.001
3–4 (%)	7	29
Exacerbations in the last year
Without admission	0 (0–1) +	1 (0–2) +	0.013
With admission	0 (0-0) +	0 (0–1) +	0.116
FRC % of predicted	142 ± 31*	134 ± 32*	0.470
IC/TLC ≤ 0.25 (%)	8 (11)	7 (10)	0.627
PaO2 (mmHg)	70 ± 11*	76 ± 11*	0.004
PaCO2 (mmHg)	45 ± 6*	40 ± 5*	<0.001
6MWD (mts)	529 ± 93*	459 ± 79*	<0.001
6MWD % of Predictive	107 ± 21*	85 ± 17*	<0.05
SGRQ
Total	26 (15–52) +	38 (30–47) +	0.011
Symptoms	39 (12–53) +	48 (32–58) +	0.028
Activity	37 (14–62) +	53 (40–62) +	0.020
Impact	15 (6–45) +	28 (13–40) +	0.013

*represents mean ± SD; + represents median and 25^th-75^th percentiles