Figure 2.

Sequences of wild type and mutant MLV and MPMV cytoplasmic tails. A. The 10 amino acids conserved between MLV and MPMV cytoplasmic tails (CT) are noted ● Bold letters indicate the position of the conserved dileucine- and tyrosine-based motifs, whereas underlined letters indicate the position of the extra tyrosine-based motif in MPMV CT. B. Sequences of the mutated CD25 chimeras that we used in this study. The mutants are named CD25-retrovirus X amino acid position Z, where X and Z are the wild-type and mutant amino-acids, respectively. The amino-acid position 1 corresponds to the first residue of the corresponding viral CT.