. Author manuscript; available in PMC: 2006 Oct 5.

Published in final edited form as: Chromosoma. 2004 May 25;112(8):398–409. doi: 10.1007/s00412-004-0285-5

Table 1.

Distribution of nuclear bodies in UR61 cells following treatment with methyltransferase inhibitors. (n=at least 200 in all groups; values are mean ± SDM) (AdOx,adenosine dialdehyde; Dex, dexamethasone; MTA, 5′-deoxy-5′-methylthioadenosine)

Cell type and treatment	Cajal bodies	Gems
UR61(0 h Dex)	1.65±0.25	0.13±0.12
UR61 (0 h Dex)+4 h MTA	1.56±0.10	0.09±0.06
UR61 (0 h Dex)+24 h MTA	1.20±0.11^a	0.30±0.15
UR61 (0 h Dex)+4 h AdOx	1.50±0.08	0.06±0.05
UR61 (0 h Dex)+24 h AdOx	1.42±0.16	0.12±0.07
UR61 (40 h Dex)	2.00±0.23	1.10±0.39
UR61 (40 h Dex)+4 h MTA	1.79±0.22	0.87±0.22
UR61 (40 h Dex)+24 h MTA	1.10±0.05^b	3.05±0.84^b
UR61 (40 h Dex)+4 h AdOx	3.08±0.24^b	0.68±0.23
UR61 (40 h Dex)+24 h AdOx	2.86±0.14^b	1.19±0.44

Significant differences (p<0.005) are found between untreated and MTA-treated groups of undifferentiated (0 h Dex) UR61 cells

Significant differences (p<0.005) are found between untreated and MTA-treated or AdOx-treated groups of differentiated (40 h Dex) UR61 cells