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. 2006 Oct 7;333(7571):740–743. doi: 10.1136/bmj.333.7571.740

Table 2.

Achievable weight change (95% confidence intervals) from meta-analyses of randomised controlled trials in adults

Weight change (kg) at 1-3 years
Trials 1 2 3
Lifestyle interventions v control



Deficit of 600 kcal/day,* or low fat diet
−5.3 (−5.9 to −4.8)
−2.4 (−3.6 to −1.2)
−3.6 (−4.5 to −2.6)
Diet and exercise
−4.8 (−5.4 to −4.2)
−2.7 (−3.6 to −1.8)
Not studied
Diet and behaviour therapy
−7.2 (−8.7 to −5.8)
−1.8 (−4.8 to 1.2)
Not studied
Diet, exercise, and behaviour therapy
−4.0 (−4.5 to −3.5)
−3.0 (−3.6 to −2.4)
−2.0 (−2.7 to −1.3)
Effect of adding exercise



Adding exercise to diet
−2.0 (−3.2 to −0.7)
Not studied
−8.2 (−15.3 to −1.2)
Adding exercise to diet, plus behaviour therapy
−3.0 (−4.9 to −1.1)
−2.2 (−4.2 to −0.1)
Not studied
Effect of adding behaviour therapy



Adding behaviour therapy to diet −7.7 (−12.0 to −3.4) Not studied −2.9 (−8.6 to 2.8)

Data from Avenell et al (see Further Reading box).

*

1 kcal = 4.18 kJ.