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. 2006 May;8(5):413–418. doi: 10.1593/neo.06139

Figure 3.

Figure 3

Complete nucleotide sequence of PPP2R2A/CHEK2 chimeric transcript 1 detected by RT-PCR. The primers PPP2R2A-242F and CHEK2-982R are underlined. Arrowheads indicate breakpoints, and vertical lines indicate exon boundaries. The inserted DNA between exon 2 of PPP2R2A and exon 4 of CHEK2 is a repetitive sequence from chromosome 22, which belongs to type 1 of ERV-related sequences. Sequence in bold (part of the inserted DNA) is absent in type 2 chimeric transcript. Sequence in brackets is not present in type 3 of the PPP2R2A/CHEK2 cDNA fragment (part of inserted sequence and exon 4 of CHEK2).