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Effect of z-VAD, the pan-caspase inhibitor, on cell growth (A), cell death (B), and caspase activity (C) in LNCaP, DU145, LAPC4, and PC3. Cells were cultured without (control), with 5 μM SAHA, with 40 μM z-VAD, and with 5 μM SAHA plus 40 μM z-VAD (combination).
