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The folding rates for various polypeptides and proteins versus the solvent viscosity: (Gly-Ser)n (n = 1 and 3) polypeptide chains (17) (from Eq. 4, κ = 0.95 and 0.80, respectively), tryptophan cage (21) (κ = 0.84), cytochrome c (14, 15) (κ = 0.55), α-helix (κ = 0.53), β-hairpin (18) (κ = 0.93), and protein L (19) (κ = 0.93). The rate coefficients for the bulk α-fluctuations for glycerol–water mixtures (kα) and for kexit also are plotted for comparison.
