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. 2006 Oct 12;116(11):2964–2971. doi: 10.1172/JCI28326

Figure 1. Autoimmunity in Nfkb2–/– mice.

Figure 1

(A) H&E staining of formalin-fixed sections of livers, lungs, kidneys, and pancreata from 6- to 8-month-old WT or Nfkb2–/– mice. Magnification, ×200. (B) Increased percentage of activated and memory T cells in the lungs of 6- to 8-month-old Nfkb2–/– mice compared with age-matched WT mice. Numbers represent the percentages within the indicated regions. Data are representative of 3 experiments. (C) Increased levels of anti-insulin IgG and IgM were detected in 6- to 8-month-old Nfkb2–/– mice compared with age-matched WT mice. *P < 0.05 versus WT. (D) Autoantibodies were determined by immunofluorescence staining of Rag1–/– tissue sections. Magnification, ×100.