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Two-locus NPL scores of the regions having strongest evidence for linkage in the initial single-locus parametric and NPL analysis. Results are shown for chromosomes 1 and 4. The arrow labeled “NPL” indicates the point associated with maximum NPL score for the two-locus analysis. The coordinate arrows indicate where the maximum two-locus NPL scores were reached, at markers D1S249 and D4S3030 (207.07 cM and 170.81 cM, respectively).
