. Author manuscript; available in PMC: 2006 Oct 10.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1496–1501. doi: 10.1158/1055-9965.EPI-04-0880

Table 4.

Joint effects of adult exercise and sport activity levels, occupational activity levels, energy intake, and BMI on breast cancer risk

	Energy intake (kcal/d)		BMI (kg/m²)
		Low (<21)	Intermediate (21 ≤ BMI ≤ 25)	High (≥25)
All women
Adult exercise/sports (MET-h/d/y)
Yes	Low (<1,794)	1.0 (Reference)	0.94 (0.52–1.71)	0.92 (0.48–1.76)
	High (>1,794)	0.74 (0.37–1.46)	0.91 (0.51–1.63)	0.81 (0.44–1.50)
No	Low (<1,794)	1.12 (0.66–1.90)	1.25 (0.75–2.09)	1.69 (0.98–2.89)
	High (>1,794)	0.93 (0.54–1.60)	1.47 (0.88–2.46)	1.79 (1.06–3.05)
P_interaction	0.65
Premenopausal
Occupational activity (h/d/y)
Yes	Low (<1,794)	1.0 (Reference)	1.12 (0.83–1.52)	1.08 (0.72–1.61)
	High (>1,794)	0.85 (0.59–1.21)	1.23 (0.90–1.68)	1.22 (0.85–1.75)
No	Low (<1,794)	1.57 (0.88–2.79)	1.48 (0.88–2.51)	2.82 (1.29–6.18)
	High (>1,794)	1.30 (0.64–2.65)	1.99 (1.13–3.53)	1.51 (0.64–3.54)
P_interaction	0.14
Postmenopausal
Adult exercise/sports (MET-h/d/y)
Yes	Low (<1,794)	1.0 (Reference)	0.90 (0.35–2.31)	1.15 (0.45–2.77)
	High (>1,794)	0.59 (0.19–1.84)	1.03 (0.43–2.51)	1.12 (0.45–2.77)
No	Low (<1,794)	1.36 (0.55–3.40)	1.59 (0.68–3.73)	2.55 (1.07–6.04)
	High (>1,794)	1.01 (0.39–2.58)	1.83 (0.79–4.25)	2.84 (1.21–6.67)
P_interaction	0.21

NOTE: Data were adjusted for age at interview, education, income, history of fibroadenoma, history of breast cancer among first-degree relatives, menopausal status, height, and ever had live birth. Occupational activity was measured as the average time spent in standing or walking and classified into one of three activity categories (i.e., heavy, medium, or nonphysical work).