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Influence of the CYP2C19 (allele *2) genotype on average steady-state plasma voriconazole concentrations as determined by a population pharmacokinetics analysis. The box-and-whisker plots display the box locations of the median, upper, and lower quartiles, with whiskers extending to the furthest data point within 1.5 times the interquartile range. The scatter of individual data is also displayed. (Reprinted from reference 78).
