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. 2006 Jul;26(14):5249–5258. doi: 10.1128/MCB.02473-05

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FIG. 5. — Analysis of M-MSV-induced tumor growth in Cybr-deficient mice. (A) Cumulative kinetics of tumor growth in Cybr knockout (filled circles) and wild-type control littermates (open circles) from three different experiments are shown. Twenty out of 23 (86.9%) Cybr-deficient and 14 out of 20 (70.0%) wild-type mice injected intramuscularly with M-MSV developed sarcomas. Tumor size (in milimeters) was monitored up to day 13, when most of animals were sacrificed. , P < 0.05 (Student t test). (B) Total number of cells in spleen and tumor-draining lymph node of tumor-bearing mice at day 13 from the M-MSV inoculation. , P < 0.05 (Mann-Whitney U test).

Inline graphic — Analysis of M-MSV-induced tumor growth in Cybr-deficient mice. (A) Cumulative kinetics of tumor growth in Cybr knockout (filled circles) and wild-type control littermates (open circles) from three different experiments are shown. Twenty out of 23 (86.9%) Cybr-deficient and 14 out of 20 (70.0%) wild-type mice injected intramuscularly with M-MSV developed sarcomas. Tumor size (in milimeters) was monitored up to day 13, when most of animals were sacrificed. , P < 0.05 (Student t test). (B) Total number of cells in spleen and tumor-draining lymph node of tumor-bearing mice at day 13 from the M-MSV inoculation. , P < 0.05 (Mann-Whitney U test).