TABLE 1.
Embryonic stage | nb | No. of crosses | No. (%) of embryos or pups with genotype
|
||
---|---|---|---|---|---|
+/+ | +/i | i/i | |||
E14.5 | 200 | 15 | 52 (26) | 104 (52) | 44 (22) |
E15.5-17.5 | 194 | 26 | 51 (25.4) | 100 (50.5) | 43 (21.4) |
P0 | 221 | 34 | 73 (33.0) | 132 (59.7) | 14 (6.3), 2 (0.9)c |
The mice employed in these crosses had been backcrossed from 7 to 9 generations with wt C57BL/6.
Numbers of embryos or newborn pups analyzed.
Two mice were born alive but died within the first day.