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mafA mRNA levels are decreased by siRNA-mediated knockdown of pdx-1. INS-1 (832/13) cells were treated with recombinant adenoviruses expressing siControl or siPDX-1. The effects on pdx-1 and mafA mRNA were analyzed by RT-PCR. The mafA and pdx-1 values are normalized to those for siControl-treated cells and presented as means ± standard errors of the means. Each experiment was performed in triplicate and repeated five times.
