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Human CD79b transgene containing the 0.2-kb minimal promoter (−0.2CD79b) maintains B-cell specificity. Total RNAs purified from the indicated tissues of a −0.2CD79b transgenic mouse (1294E) were analyzed by Northern blot hybridization. A human-specific CD79b probe was used to detect hCD79b mRNA. The level of mouse 18S rRNA served as a loading and transfer control.
