FIG. 6.
NBS1 is not required for DNA damage-inducible phosphorylation of FANCD2 on T691. The indicated EBV-transformed human lymphoblast lines were exposed to either IR, MMC, or HU, as indicated. PD20 (FA-D2) fibroblasts, expressing wild-type FANCD2, were also analyzed. Proteins from whole-cell extracts were immunoblotted with antisera specific for either pT691 or unphosphorylated FANCD2.