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Expression of Cμ poly(A) signal mutations in stable B-cell and plasma cell lines
| Construct | pA/splice ratio (avg ± SD)a
|
Ratio of PC/B regulation | |
|---|---|---|---|
| B cell | PC | ||
| Cμ | 3.9 ± 0.2 | 44 ± 3 | 11 |
| ΔU | 3.7 ± 0.5 | 39 ± 5 | 11 |
| ΔU1 | 0.51 ± 0.04 | 6.7 ± 0.3 | 13 |
| ΔU2 | 0.34 ± 0.02 | 5.1 ± 0.5 | 15 |
| ΔU1GU | 0.61 ± 0.04 | 2.7 ± 0.2 | 4 |
| ΔU2ptGU | 0.50 ± 0.07 | 4.6 ± 0.3 | 9 |
| GU3 | 3.7 ± 0.2 | 43 ± 4 | 12 |
The expression ratios were compiled from at least three independent S1 analyses of RNA from stably transfected cell lines.
