TABLE 2.

High levels of cytoplasmic MDM2 and low levels of membrane-associated E-cadherin are associated with an increased risk for axillary lymph node metastasis in breast cancer patients^a

Term	Odds ratio	95% confidence interval	P value
E-cadherin (low vs high)	2.83	0.81, 9.9	0.010
MDM2 (high vs low)	1.26	0.45, 3.54	0.66
E-cadherin and MDM2	6.83	1.42, 32.78	0.02

^aA logistic regression analysis was performed to determine if levels of E-cadherin, MDM2, or both conferred an increased risk for axillary lymph node metastasis. The odds ratios and 95% confidence intervals are shown. The reverse correlation between E-cadherin and MDM2 is significantly associated with an increased risk of ALN metastasis (P = 0.02).