FIG. 2.

Abrogation of foxl1 function by MO antisense oligonucleotide. (A to D) Control or foxl1 MO was injected into fertilized eggs at the one- or two-cell stage, and embryos were examined at various stages. Lateral views (anterior at the top) of embryos at 27 hpf (A) and dorsal views (anterior to the left) of embryos at 72 hpf (B) injected with control MO or foxl1 MO. The arrowheads in panel B indicate the position of pectoral fin. (C and D) Craniofacial development in foxl1 MO-injected embryos. Alcian blue-stained control (C) and foxl1 (D) MO-injected embryos at 5 dpf are shown. Lateral views with anterior to the left (left panels) and ventral views with anterior to the left (right panels) are seen. Abbreviations: bh, basihyal; cb, ceratobranchial; ch, ceratohyal; hs, hyosymplectic; pq, palatoquadrate. Scale bars, 100 μm.