Table 2.
Significance of miRNA target predictions based on miRNA microarray perturbation data.
| Down-regulated genes | With 3'UTR | miTarget | Common | P-values | |
|---|---|---|---|---|---|
| miR-1 | 96 | 66 | 2,295 | 24 | 9.47E-08 |
| miR-124a | 174 | 117 | 3,048 | 36 | 1.02E-05 |
| miR-373 | 65 | 40 | 2,964 | 15 | 2.62E-04 |
The downregulated gene # is the number of genes downregulated by overexpression of each miRNA, reported in Lim's paper [40] and "With 3'UTR" indicates the number of downregulated genes with a 3'UTR sequence. The "miTarget" is the number of target gene candidates predicted by miTarget; the "Common" means the number of candidates shared by "With 3'UTR". The P-value was calculated by hypergeometric testing.