TABLE 2.
Substrate(s) | Amino acid modification sites | Functional relevance | References |
---|---|---|---|
Histone H1 (H1.1, H1.2, H1.3, H1.4, H1.5) | Glutamic acid residues E2 (all), E15 (all), E114 (H1.2), E115 (H1.3/H1.4), E117 (H1.5); arginine residue R33 (H1.3); phosphoserine residues(?) | NAa | 293, 308, 335, 373, 389, 416 |
Histone H2A | Glutamic acid residues, arginine residues, phosphoserine residues (?) | NA | 141, 308, 373, 389 |
Histone H2B | Glutamic acid residue E2, arginine residues, phosphoserine residues (?) | NA | 55, 292, 308, 373, 389 |
Histone H3 | Arginine residues, phosphoserine p-S57 (?) | NA | 141, 308, 373, 389 |
Histone H4 | Arginine residues, phosphoserine residues (?) | NA | 141, 308, 373, 389 |
High-mobility-group proteins HMGA1a, HMGA1b, HMGA2, MGB1, HMGB2, HMGN1, HMGN2 | Arginine and glutamic acid residues (?) | NA | 117, 148, 394-396, 405 |
Low-mobility-group proteins (?) |
NA, not analyzed.