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Three major classes of eukaryotic zinc finger proteins
| Zinc finger class | Subclass(es) | Consensus amino acid sequence | Example |
|---|---|---|---|
| I (C2H2) | FOG (C2HC) | Cys-X2-4-Cys-X12-His-X3-5-His | Xenopus TFIIIA |
| II (C4) | GATA, nuclear receptors, LIM (C3H) | Cys-X2-Cys-Xn-Cys-X2-Cys-Xn-Cys-X2-Cys-Xn-Cys-X2-Cys | Glucocorticoid receptor |
| III (C6) | Cys-X2-Cys-X6-Cys-X5-12-Cys-X2-Cys-X6-8-Cys | S. cerevisiae Gal4p |
