TABLE 11.
Composition of the variant exoproteome of sequenced S. aureus strains
| Identification no. | Protein | Function | Presence of protein in straina
|
|||||
|---|---|---|---|---|---|---|---|---|
| COL | MRSA252 | MSSA476 | Mu50 | MW2 | N315 | |||
| 15925799 | Plc | 1-Phosphatidylinositol phosphodiesterase precursor | Y | Y | N | Y | Y | Y |
| 15926099 | Set6 | Exotoxin 6 | N | N | N | Y | N | Y |
| 15926100 | Set7 | Exotoxin 7 | Y | N | Y | Y | Y | Y |
| 15926101 | Set8 | Exotoxin 8 | N | N | Y | Y | Y | Y |
| 15926103 | Set10 | Exotoxin 10 | N | Y | Y | Y | Y | Y |
| 15926104 | Set11 | Exotoxin 11 | N | Y | Y | Y | Y | Y |
| 15926105 | Set12 | Exotoxin 12 | N | N | Y | Y | Y | Y |
| 15926106 | Set13 | Exotoxin 13 | Yb | Y | Y | Y | Y | Y |
| 15926111 | Set15 | Exotoxin 15 | N | N | N | Y | N | Y |
| 15926113 | SA0395 | Hypothetical protein | Y | Y | Y | N | Y | Y |
| 15926465 | SA0743 | Hypothetical protein | Y | N | Y | Y | Y | Y |
| 15926739 | SA1001 | Hypothetical protein | Y | N | Y | Y | Y | Y |
| 15926746 | HlY | α-Hemolysin precursor | Y | N | Y | Y | Y | Y |
| 15927016 | EbhB | Hypothetical protein | Y | Y | N | Y | Y | Y |
| 15927308 | Fhs | Hypothetical protein | Y | N | Y | Y | Y | Y |
| 15927386 | SplB | Serine protease SplB | Y | N | Y | Y | Y | Y |
| 15927387 | SplA | Serine protease SplA | Y | N | Y | Y | Y | Y |
| 15927389 | SA1633 | Probable β-lactamase | N | N | N | Y | N | Y |
| 15927393 | LukD | Leukotoxin, LukD | Y | N | Y | Y | Y | Y |
| 15927398 | SEG | Extracellular enterotoxin type G precursor | N | Y | N | Y | N | Y |
| 15927399 | SEN | Enterotoxin SEN | N | Y | N | Y | N | Y |
| 15927402 | SEI | Extracellular enterotoxin type I precursor | N | Y | N | Y | N | Y |
| 15927404 | SEO | Enterotoxin SEO | N | Y | N | Y | N | Y |
| 15927512 | Map | Truncated MapW protein | Y | Y | N | Y | Y | Y |
| 15927513 | Hlb | β-Hemolysin/phospholipase C | Y | N | N | Y | Y | Y |
| 15927516 | SA1754 | Hypothetical protein | N | Y | Y | Y | Y | Y |
| 15927517 | SA1755 | Hypothetical protein | N | Y | N | N | N | Y |
| 15927520 | Sak | Staphylokinase precursor | N | Y | Y | Y | Y | Y |
| 15927522 | SA1760 | Hypothetical protein | N | Y | Y | Y | Y | Y |
| 15927585 | SEC3 | Enterotoxin type C3 | Y | Y | N | Y | Y | Y |
| 15927586 | SA1818 | Hypothetical protein | Y | N | N | Y | Y | Y |
| 15927587 | TSST-1 | Toxic shock syndrome toxin 1 | N | N | N | Y | N | Y |
| 15927741 | FmtB | FmtB protein | Y | N | N | Y | Y | Y |
| 15928076 | SA228 | Hypothetical protein | Y | N | Y | Y | Y | Y |
| 15928174 | SA2381 | Hypothetical protein | N | N | Y | Y | Y | Y |
| 15928182 | SA2389 | Hypothetical protein | N | N | N | Y | N | Y |
| 16119219 | SAP019 | Hypothetical protein | N | Y | Y | N | N | Y |
| 14141830 | SAVP008 | Hypothetical protein | N | N | N | Y | N | N |
| 21282111 | Set16 | Hypothetical protein | N | Y | Y | N | Y | N |
| 21282116 | Set21 | Hypothetical protein | N | N | Y | N | Y | N |
| 21282123 | Set26 | Hypothetical protein | N | Y | Y | N | Y | N |
| 21283107 | LukF | Panton-Valentine leukocidin chain F precursor | N | N | N | N | Y | N |
| 21283108 | LukS | Panton-Valentine leukocidin chain S precursor | N | N | N | N | Y | N |
| 21284341 | Cna | Collagen adhesin precursor | N | Y | Y | N | Y | N |
| 49482651 | SAR0423 | Exotoxin | N | Y | N | N | N | N |
| 49482652 | SAR0424 | Exotoxin | N | Y | N | N | N | N |
| 49482653 | SAR0425 | Exotoxin | N | Y | N | N | N | N |
| 49482925 | SAR0721 | Multicopper oxidase protein | N | Y | N | N | N | N |
| 49484047 | SAR1886 | Putative exported protein | N | Y | N | N | N | N |
| 49484059 | SAR1905 | Serine protease | N | Y | N | N | N | N |
| 49484898 | SAR2788 | Putative exported protein | N | Y | N | N | N | N |
| 49484957 | SEH | Enterotoxin H | N | N | Y | N | Y | N |
| 49485293 | SAS0389 | Exotoxin | N | N | Y | N | Y | N |
| 57650600 | SACOL1865 | Serine protease SplE, putative | Y | Y | N | N | N | N |
| 57650605 | SACOL1870 | Hypothetical protein | Y | N | Y | N | Y | N |
| 57650609 | EpiP | Epidermin leader peptide processing serine protease EpiP | Y | N | Y | N | Y | N |
| 57651309 | SACOL0468 | Exotoxin 3, putative | Y | N | N | N | N | N |
| 57651311 | SACOL0470 | Exotoxin, putative | Y | N | N | N | N | N |
| 57651319 | SACOL0478 | Exotoxin 3, putative | Y | N | N | N | N | N |
| 57652419 | Pls | Methicillin-resistant surface protein | Y | N | N | N | N | N |
a
Y, yes; N, no.
b
This protein has a Thr at the +1 position, which is not included in the SpsB recognition and cleavage pattern. All other S. aureus strains conform to the proposed pattern.