TABLE 8.
Core lipoproteome of S. aureus, defined as proteins with predicted lipoprotein signal peptides present in all sequenced strains
| Identification no. | Protein | Amino acid at position:
|
Function | ||||
|---|---|---|---|---|---|---|---|
| −3 | −2 | −1 | +1 | +2 | |||
| 15925800 | SA0092 | T | A | G | C | G | Hypothetical protein |
| 15925819 | SirA | L | A | G | C | S | Lipoprotein |
| 15925847a | SA0138 | A | A | A | C | G | Hypothetical protein, similar to alkylphosphonate ABC transporter |
| 15925912 | Slp | L | S | G | C | G | RGD-containing lipoprotein |
| 15925918 | SA0207 | V | T | A | C | G | Hypothetical protein, similar to maltose/maltodextrin-binding protein |
| 15925928a,b | SA0217 | L | S | S | C | A | Hypothetical protein, similar to periplasmic-iron-binding protein BitC |
| 15925940c | SA0229 | L | S | G | C | G | Hypothetical protein, similar to nickel ABC transporter nickel-binding protein |
| 15926044 | SA0331 | I | A | A | C | G | Conserved hypothetical protein |
| 15926073 | SA0359 | L | T | A | C | G | Conserved hypothetical protein |
| 15926079a | SA0363 | L | T | G | C | A | Hypothetical protein |
| 15926141a,d | SA0422 | L | A | A | C | G | Hypothetical protein, similar to lactococcal lipoprotein |
| 15926287a | SA0566 | L | S | G | C | G | Hypothetical protein, similar to iron-binding protein |
| 15926308a | SA0587 | V | A | A | C | G | Lipoprotein, streptococcal adhesin PsaA homologue |
| 15926354a | SA0632 | L | T | G | C | G | Conserved hypothetical protein |
| 15926385a,e | SA0663 | L | G | A | C | G | Hypothetical protein |
| 15926413a,f | SA0691 | L | A | A | C | G | Lipoprotein, similar to ferrichrome ABC transporter |
| 15926417a | SA0695 | I | S | A | C | G | Hypothetical protein |
| 15926461 | SA0739 | L | G | A | C | G | Conserved hypothetical protein |
| 15926499a,g | SA0771 | L | A | A | C | G | Conserved hypothetical protein |
| 15926579a | SA0849 | L | S | G | C | A | Hypothetical protein, similar to peptide binding protein OppA |
| 15926625 | SA0891 | V | A | G | C | G | Hypothetical protein, similar to ferrichrome ABC transporter |
| 15926678a | SA0943 | L | A | G | C | T | Conserved hypothetical protein |
| 15926717h | IsdE | L | T | S | C | Q | Hypothetical protein |
| 15926796a | SA1056 | V | A | G | C | S | Hypothetical protein |
| 15926969h | SA1221 | L | G | A | C | G | Thioredoxin reductase |
| 15927111a,e | SA1361 | L | A | G | C | G | Hypothetical protein |
| 15927372h | SA1616 | L | S | S | C | G | Hypothetical protein |
| 15927375a | SA1619 | L | T | A | C | G | Hypothetical protein |
| 15927415a | PrsA | L | G | A | C | G | Peptidyl-prolyl cis/trans isomerase homolog |
| 15927477a | SA1719 | L | A | A | C | G | Conserved hypothetical protein |
| 15927757a,i | SA1979 | V | A | A | C | G | Hypothetical protein, similar to ferrichrome ABC transporter (binding protein) |
| 15927864g | SA2079 | L | A | A | C | G | Hypothetical protein, similar to ferrichrome ABC transporter FhuD precursor |
| 15927948a | SA2158 | L | A | A | C | G | Hypothetical protein, similar to TpgX protein |
| 15927961a,h | SA2171 | L | I | V | C | I | Hypothetical protein |
| 15927984a | DsbA | L | A | A | C | G | DsbA; hypothetical protein similar to Zn-binding lipoprotein AdcA |
| 15927987c | SA2197 | L | T | A | C | G | Conserved hypothetical protein |
| 15927988c | SA2198 | I | S | G | C | G | Hypothetical protein |
| 15927992a,g | SA2202 | L | A | A | C | G | Hypothetical protein, similar to ABC transporter, periplasmic amino acid-binding protein |
| 15928025a | OpuCC | L | S | G | C | S | Glycine betaine/carnitine/choline ABC transporter OpuC |
| 15928037a | SA2247 | L | S | A | C | G | Conserved hypothetical protein |
| 15928046a | Opp-1A | L | T | G | C | G | Oligopeptide transporter putative substrate binding domain |
| 15928066a,i | SA2275 | I | G | A | C | G | Hypothetical protein |
| 15928267h | SA2473 | L | Y | S | C | S | Hypothetical protein |
Also present in S. epidermidis.
Excluded for S. aureus Mu50 and N315 because of the motif proposed by Sutcliffe and Harrington (171).
Excluded for S. epidermidis because of the motif proposed by Sutcliffe and Harrington (171).
Contains the lipoprotein release motif (179) with one amino acid change, except for S. aureus COL and S. epidermidis.
Contains the lipoprotein release motif (179) with one amino acid change for all staphylococcal strains.
Contains the exact lipoprotein release motif (179), except in S. epidermidis.
Contains the lipoprotein release motif (179) with one amino acid change, except in S. epidermidis.
Excluded for all S. aureus strains because of the motif proposed by Sutcliffe and Harrington (171).
Contains the lipoprotein release motif (179) with one amino acid change, only for S. epidermidis.