FIG. 2.

Analysis of sera for antibodies against HSV-1 and/or HSV-2. An analysis of sera by WB-UB for antibodies against HSV-1 and/or HSV-2, as related to age groups, is shown in panel B. Statistical methods were used to investigate whether the differences in prevalence between the age groups were significant. For HSV-1 antibodies, the results were as follows: χ² = 15.68, df = 4, and P = 0.003. For HSV-2 antibodies, the results were as follows: χ² = 27.72, df = 4, and P < 0.001. The horizontal bars for the 1- to 4-year-old age group indicate the prevalence of HSV-1 and HSV-2 antibodies, respectively, in the subgroup of 2- to 4-year-olds. In panel A, the 1- to 4-year-old age group is split into two subgroups, <2 years and 2 to 4 years. Statistical methods were used to analyze the differences between the age groups. For HSV-1 antibodies, the results were as follows: P = 0.80 and OR (95% CI) = 1.14 (0.43 to 3.01). For HSV-2 antibodies, the results were as follows: P < 0.001 and OR (95% CI) = 0.12 (0.04 to 0.36). Panel C shows the percentages of uninfected and single- and double-infected individuals in each age group.