TABLE 1.
Gene | Position on codon | WT amino acida | Mutant amino acid(s) | Gene | Position on codon | WT amino acida | Mutant amino acid(s) | |
---|---|---|---|---|---|---|---|---|
Pol | tp17 | G | Del | s207 | V | I, M, L, E | ||
tp18 | T | Del | s210 | S | T, R, N | |||
sp8 | V | D, F, S, L | s213 | I | M, L | |||
sp35 | A | D, V, S, T | s216 | L | -, S | |||
rt70 | T | S | s220 | F | C, L | |||
rt71 | N | T | s229 | L | V, M | |||
rt86 | A | P | s306 | P | S | |||
rt92 | P | L | Core | BCP 1752 | A | T, G, C | ||
rt100 | H | R, N | BCP 1753 | T | A, C, G | |||
rt102 | L | I, V | BCP 1754 | T | C, G | |||
rt115 | L | V | BCP 1757 | G | A | |||
rt128 | T | N, A | BCP 1762 | A | T | |||
rt133 | H | Q | BCP 1764 | G | A | |||
rt135 | S | H, Y, C | BCP 1766 | C | T, G | |||
rt153 | W | Q, R | BCP 1768 | T | A | |||
rt173 | V | L, G | BCP 1770 | G | T | |||
rt177 | P | L | BCP 1802 | C | T | |||
rt180 | L | M, L | BCP 1803 | G | T, C | |||
rt181 | A | G | BCP 1809 | G | T | |||
rt184 | T | N, S | BCP 1810 | C | T | |||
rt190 | V | M, I | BCP 1811 | A | C, G | |||
rt204 | M | V, I | BCP 1812 | C | T | |||
rt207 | V | I, M, L, E | BCP 1748-1758 | Del | ||||
rt212 | K | R | BCP 1750-1770 | Del | ||||
rt213 | S | T, N | BCP 1753-1772 | Del | ||||
rt217 | R | L | BCP 1755-1759 | Del | ||||
rt229 | L | V, M | BCP 1755-1771 | Del | ||||
rt331 | L | P | BCP 1755-1774 | Del | ||||
rt332 | S | C | BCP 1766-1773 | Del | ||||
rt336 | M | L, Q, I | BCP 1758-1765 | Del | ||||
S | pre-S1 5 | S | Y, L, T | BCP 1759-1766 | Del | |||
pre-S2 1 | M | V | BCP 1760-1765 | Del | ||||
pre-S2 13 | Q | L, T, I | BCP 1757-1777 | Del | ||||
s40 | N | S | BCP 1763-1770 | Del | ||||
s85 | F | C | BCP 1765-1772 | Del | ||||
s96 | V | G | BCP 1767 | Ins | ||||
s98 | L | V | BCP 1767-1774 | Del | ||||
s100 | Y | C, F | BCP 1768-1774 | Del | ||||
s101 | Q | K, R | BCP 1770-1776 | Del | ||||
s110 | I | T, L | pre-C 1 | M | -, L, P, K, T, R, I | |||
s114 | T | S, Q | pre-C 2 | Q | -, L, R | |||
s115 | T | A, Q | pre-C 9 | I | T, N | |||
s118 | T | M, V | pre-C 11 | S | L | |||
s120 | P | T, Q | pre-C 13 | T | T, S, L | |||
s121 | C | R | pre-C 15 | P | S, L | |||
s122 | K | R | pre-C 16 | T | I | |||
s123 | T | I, N | pre-C 17 | V | F, L | |||
s125 | T | M, L | pre-C 21 | K | - | |||
s126 | T | I, S, A | pre-C 25 | G | G | |||
s127 | P | S, T, L | pre-C 28 | W | R, - | |||
s128 | A | V | pre-C 29 | G | S, D | |||
s129 | Q | N, H, R, K, L | C2 | D | Ins | |||
s130 | G | N, R, E, D, S | C5 | P | T, S, A | |||
s131 | N | T | C27 | V | I, N | |||
s134 | F | I, Y, L | C36 | A | Del | |||
s138 | C | Y, W | C38 | Y | H, D, F | |||
s140 | T | S, I | C40 | E | D, N, T | |||
s141 | K | E | C60 | L | V, I | |||
s142 | P | S | C 77 | E | D, N, Q, A | |||
s143 | T | M, S, L | C 84 | L | S, A, Q | |||
s144 | D | A, E | C 97 | I | L, F | |||
s145 | G | R, K | C 130 | P | T, I, L, S, Q | |||
s146 | N | S | X | x26 | R | C, S, H | ||
s157 | A | D, V, G | x30 | L | V, F, I | |||
s158 | F | L, S | x80 | E | R, K, A | |||
s159 | A | G | x82 | T | A, S | |||
s160 | K | R | x86 | H | S, P, R, N, D | |||
s161 | Y | F | x87 | Q | R, H, W, M, L, G, - | |||
s168 | V | A, I | x88 | I | N, H, S, G, F, V, A, M | |||
s171 | S | Y | x94 | H | Y | |||
s172 | W | - | x101 | P | S, F, A, T | |||
s175 | L | S | x102 | A | G, V, S, T | |||
s178 | P | Q | x103 | A | K, E, D | |||
s189 | T | I | x116 | V | L | |||
s192 | L | P | x123 | L | S, F | |||
s196 | W | L | x125 | E | N, G, A | |||
s198 | M | I | x127 | I | S, M, N, L, G, V, F, T | |||
s199 | W | - | x130 | K | M | |||
s204 | S | R, N, G, L | x131 | V | T, I, S | |||
s205 | L | R | x144 | A | S, V, P |
The wild-type (WT) sequence is that of genotype A (GenBank accession number X02763).
Del, deletion; Ins, insertion; -, no amino acid.