TABLE 2.
In vitro susceptibilities of reference type Malassezia isolates to three antifungal agents as determined by the modified urea and CLSI broth microdilution methodsa
| Isolate | MIC range (μg/ml)
|
||
|---|---|---|---|
| Voriconazole | Itraconazole | Ketoconazole | |
| M. furfur CBS 7019b | 0.125-0.5 | 0.125-0.25 | 0.125-0.5 |
| M. globosa CBS 7966c | 0.5-2.0 | 2.0-8.0 | 1.0-4.0 |
| M. restricta CBS 7877c | 0.06-0.25 | 0.5-4.0 | 1.0-2.0 |
| M. sympodialis CBS 7222b | 0.125-0.5 | 0.06-0.25 | 0.25-1.0 |
| M. pachydermatis CBS 1879b | 0.25 | 0.06 | 0.25 |
| M. obtusa CBS 7876b | ≤0.03-0.03 | 0.125-0.25 | 0.03-0.125 |
a
Results were obtained on two to nine different days for the six species with Christensen's urea supplemented with 0.1% Tween 80 and 0.5% Tween 40, pH 5.2.
b
Results were obtained at 72 h.
c
Results were obtained at 96 h.