TABLE 5.
Kappa values and P values by McNemar's test for individual HPV genotypes detectable by both assaysa
Oncogenic potential | Genotype | No. of genotypes found positive by:
|
κ value (95% CI)b | P value (McNemar's test) | ||
---|---|---|---|---|---|---|
LiPA | LA | LiPA and LA | ||||
High risk | 16 | 39 | 45 | 38 | 0.874 (0.788-0.959)d | 0.08 |
18 | 14 | 15 | 13 | 0.887 (0.760-1.014)d | 1.00 | |
31 | 13 | 13 | 11 | 0.833 (0.672-0.995)d | 0.62 | |
33 | 10 | 9 | 8 | 0.833 (0.645-1.020)d | 1.00 | |
35 | 9 | 8 | 8 | 0.938 (0.817-1.059)d | 1.00 | |
39 | 7 | 9 | 7 | 0.869 (0.687-1.050)d | 0.48 | |
45 | 5 | 8 | 5 | 0.761 (0.492-1.029)e | 0.25 | |
51 | 16 | 11 | 11 | 0.799 (0.626-0.973)e | 0.07 | |
52 | 23 | 21 | 20 | 0.896 (0.795-0.997)d | 0.62 | |
56 | 12 | 9 | 8 | 0.747 (0.528-0.965)e | 0.37 | |
58 | 8 | 11 | 8 | 0.833 (0.646-1.020)d | 0.25 | |
59 | 6 | 11 | 6 | 0.692 (0.426-0.958)e | 0.07 | |
Probable hr | 53 | 20 | 17 | 16 | 0.848 (0.718-0.979)d | 0.37 |
66 | 9 | 8 | 7 | 0.814 (0.606-1.023)d | 1.00 | |
Low risk | 6 | 11 | 9 | 9 | 0.894 (0.748-1.040)d | 0.48 |
11 | 4 | 3 | 2 | 0.563 (0.072-1.053)f | 1.00 | |
40 | 0 | 0 | 0 | |||
42 | 2 | 7 | 2 | 0.434 (−0.055-0.923)f | 0.07 | |
54 | 9 | 18 | 8 | 0.562 (0.311-0.812)f | 0.02 | |
70 | 6 | 6 | 6 | 1.000 (1.000-1.000)c |
The results for 112 concordant, 36 compatible, and 22 discordant samples after initial analysis are shown.
CI, confidence interval.
Strength of agreement considered perfect.
Strength of agreement considered very good.
Strength of agreement considered good.
Strength of agreement considered moderate.