TABLE 3.
Relative sensitivities and specificities of TMA and PCR tests by specimen type or combination of specimen types
| Specimen tested | Relative sensitivitya (% [no.] positive)
|
Relative specificityb (% [no.] positive)
|
||
|---|---|---|---|---|
| TMA (n = 43) | PCR (n = 43) | TMA (n = 244) | PCR (n = 244) | |
| Single specimen | ||||
| Vaginal swab | 84 (36) | 91 (39) | 99.6 (243) | 100 (244) |
| Cervical swab | 60 (26) | 53 (23) | 100 (244) | 99.6 (243) |
| Urine | 58 (25) | 65 (28) | 100 (244) | 99.6 (243) |
| Two specimens | ||||
| Vaginal swab and urine | 91 (39) | 93 (40) | 99.6 (243) | 99.6 (243) |
| Vaginal and cervical swabs | 95 (41) | 95 (41) | 99.6 (243) | 99.6 (243) |
| Cervical swab and urine | 74 (32) | 77 (33) | 99.6 (243) | 99.6 (243) |
| All three specimens | 95 (41) | 98 (42) | 99.6 (243) | 99.2 (242) |
a
The relative sensitivity was calculated as the number of specimens positive for M. genitalium for each specimen type or combination of specimen types relative to the total number of women positive at any site by the TMA assay or at any site by PCR.
b
The relative specificity was calculated as the number of specimens negative for M. genitalium for each specimen type or combination of specimen types relative to the total number of women positive at any site by the TMA assay and at any site by PCR.