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. 2006 Oct;44(10):3510–3516. doi: 10.1128/JCM.00670-06

FIG. 2.

FIG. 2.

Base differences in the 16S rRNA genes of type strains formatted to emphasize the differences within each of the three clades of Leptospira. Path, pathogenic clade; Int, intermediate clade; NonP, nonpathogenic clade. Vertical numbers show the relative positions in L. interrogans AY631894. Center dots indicate the same base as L. interrogans; a dash indicates a gap. The A at position 57 in L. alexanderi would be inserted between 56 and 57 in the L. interrogans AY631894 sequence. The sequences indicate differences within each clade but do not include all differences between clades. Note that positions 95, 154, 158, 222, and 952 appear twice, and position 1077 appears in all three clades. There are >160 other positions that can be used to differentiate between Leptospira clades.