TABLE 2.
Bacterial incidence in mice at different times postwithdrawal
| Tissue | Day(s) post-WD | No. positive/total tested
|
|
|---|---|---|---|
| Placebo WD | Morphine WD | ||
| MLN | 1 | 1/5 | 5/5 |
| 3 | 0/5 | 2/5 | |
| 6 | 0/5 | 1/5 | |
| Liver | 1 | 0/5 | 3/5 |
| 3 | 0/5 | 3/5 | |
| 6 | 0/5 | 2/5 | |
| Blood | 1 | 0/5 | 1/5 |
| 3 | 0/5 | 1/5 | |
| 6 | 0/5 | 2/5 | |
| Total | 1/45 (2.2%)a | 20/45 (44.4%)a | |
P < 0.01 for placebo withdrawal (WD) versus morphine WD.