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. 2006 Sep;74(9):5177–5184. doi: 10.1128/IAI.00713-06

FIG. 2.

FIG. 2.

Infectivity and ospC expression of transformants in SCID mice. (A) Groups of 10 BALB/c SCID mice were infected with either transformant 5A13/pBBE22 or 5A13/pBBE22-ospC′ for 1 month. DNA samples were prepared from heart, joint, and skin specimens and analyzed for spirochete flaB and murine actin DNA copies by qPCR. The data are expressed as spirochete numbers per 106 host cells. (B) RNA samples were prepared from the heart, joint, and skin tissues and quantified for flaB and ospC expression by RT-qPCR. The data are presented as ospC mRNA copy numbers per 1,000 flaB transcripts.