FIG. 2.

Corneal inflammation in C57BL/6 and TLR2^−/− mice induced by S. aureus strain 8325-4. Corneas of control C57BL/6 mice and TLR2^−/− mice were abraded and exposed to either heat- or UV-inactivated S. aureus strain 8325-4. After 24 h, mice were sacrificed and examined by in vivo confocal microscopy to measure corneal thickness and haze. Neutrophils were detected in 5-μm corneal sections by immunohistochemistry and counted from limbus to limbus. (A and B) Neutrophils in C57BL/6 mice and TLR2^−/− mice. (C and D) Corneal haze. (E and F) Corneal thickness. Data are the means ± standard errors of the means (SEM) (error bars) of five mice per group. P values are noted. Experiments were repeated with similar results.