TABLE 1.
Effect of reduced levels of eosinophils (treatment with anti-CCR3 MAb) or neutrophils (CXCR2−/− mice) on the survival of S. stercoralis L3 implanted in diffusion chambers in naïve mice for 5 days
| Strain | Cell deficiency | % Survival | Total cells in diffusion chamber (mean ± SD)
|
||
|---|---|---|---|---|---|
| Neutrophils (104) | Macrophages (104) | Eosinophils (102) | |||
| C57BL/6 | 25 ± 18 | 31 ± 23 | 32 ± 25 | 62 ± 90 | |
| C57BL/6 | Eosinophils | 44 ± 18a | 24 ± 24 | 19 ± 18 | 0 ± 0a |
| BALB/c | 18 ± 7 | 73 ± 21 | 38 ± 9 | 47 ± 66 | |
| BALB/c | Eosinophils | 55 ± 9a | 78 ± 84 | 35 ± 18 | 0 ± 0 |
| CXCR2−/− | Neutrophils | 60 ± 20a | 4 ± 4a | 97 ± 39 | 59 ± 82 |
a
The value is statistically significantly different from the value for control and cell-deficient mice.